I don’t understand your question. You can use WinpkFilter to send packet to the real interface. VirtNet is just a simple dummy network inetrface with no real functionality. But in combination with WinpkFilter it can be used for building virtual networks.
Yes, this is possible using WinpkFilter. You can bridge VirtNet adapter to the real network with WinpkFilter or emulate virtual network with WinpkFilter. However, note that if you use bridging and want your real card to receive packets for the VirtNet card MAC address then your real card must be in promiscuos mode.